Roads already treacherous after heavy snow this weekend throughout the Midwest are only worsening with temperatures dipping to record lows, creating a dicey situation with black ice on the pavement.
"It's been tough. Just about 40 miles-an-hour," said Gary Wilson who is trying to get to Pennsylvania from his home in northwest Indiana. "I got it locked in four-wheel drive and just taking my time. And there aren't many cars on the highway so things have been moving pretty good."
Illinois State Police spokesman Ted Rose told ABC News Monday his district, in central Illinois, received nearly a thousand calls from stranded motorists.
"As soon as we get the interstate open back up again, if you get two or three semis jackknifed, or even one jackknife across the roadway, it just shuts everything down," Rose said.
Air traffic was once again snarled Monday, following a weekend of travel disruption across the U.S. More than 4,500 flights were canceled Monday and 13,780 delays, according to FlightAware.com.
More than 2,000 slights have already been canceled today and another 1,400 delayed, FlightAware.com report.
ABC News' Alex Perez, ABC News Radio and The Associated Press contributed to this report.