This twister was the latest in a group of violent storms that swept through the Midwest, starting Sunday, that has now left dozens of people dead.
On Sunday, a tornado ripped through Shawnee, Okla., killing a 79-year-old man near a mobile home park that was reduced to rubble, according to Pottawatomie County Sheriff Mike Booth.
Twisters, hail and high winds also struck Iowa and Kansas as part of a devastating, northeastward-moving storm system that stretched from Texas to Minnesota. Kansas, Illinois, Iowa, Missouri, Nebraska and Oklahoma were ravaged by 50 tornadoes this weekend.
Moore was the site of one of the most destructive tornadoes in U.S. history. On May 3, 1999, an EF-5 tornado ripped through the Oklahoma City area, killing 42 people.
ABC News' Mike Boettcher, Howard Price, Dan Childs, Anthony Castellano, Maria Nikias and ABC News Radio contributed to this report.